GMC Sierra 2500 HD Spark Plug Wires and Ignition Wiring
This page brings together spark plug wires and ignition wiring for the GMC Sierra 2500 HD, covering model years 2001–2022. The range includes complete wire sets, individual spark plug wires, and boot kits in OE-replacement and performance styles. Select your year above and we'll show only the spark plug wires and ignition wiring that fit your GMC Sierra 2500 HD. Fitment is checked against our vehicle data for every part listed.
Taylor Made 79214 409 Pro Race 10.4mm High-Performance Spark Plug Wires
Edelbrock 22716 Max-Fire Ultra-Spark 50 GM LS Truck Spark Plug Wire Set
Taylor 79603 409 Pro Race Ignition Wire Set Silicone Spark Plug Wires
MSD 5574 Street Fire Spark Plug Wire Set GM LS Truck 4.8L 5.3L 6.0L
FAST 255-2420 FireWire LS Series Spark Plug Wire Set GM Truck 4.8L 5.3L 6.0L 6.2L
What's here for your GMC Sierra 2500 HD
- Spark Plug Wire Sets — complete sets in OE-replacement and performance configurations, including ceramic-coated options
- Spark Plug Wires — individual wires available in multiple styles including black performance designs
- Spark Plug Boot Kits — ceramic and standard boot kits for replacing worn or damaged wire ends
The widest selection here comes from TAYLOR, Standard Motor Products, MSD, and Delphi, spanning performance and OE-style fitments across the 2001–2022 model range. Other categories GMC Sierra 2500 HD owners shop for: GMC Sierra 2500 HD Shocks and Struts, GMC Sierra 2500 HD Exterior Lights and GMC Sierra 2500 HD Springs and Suspension Parts, or browse all GMC Sierra 2500 HD parts and accessories.